Good detailed instructions, got it working on my Windows 10 Pro 64 bit system pretty much first go thanks. I installed it under a "regular" (not admin) user (but I had to be Admin to do the registry edit).
Couple of weird things I could use help with:
When I run the game it changes my Windows colour scheme to green, anyone got any idea why?
The Error messages in the registry entry for missing/wrong etc DVD seem to be irrelevant. If I run it without the DVD or with a random DVD in the drive, the error messages from the game are not those from the registry entry.
Which leads me to my main problem: I decided to create a separate Windows user (Gamer) just to play this and other driving games, this would be neat to allow guests (grand Kids) to play without them being likely to mess up any of my user's settings, files etc. Also it would hopefully get me round the annoying colour scheme change. But when I try to run the game from this user, I keep getting the Please Insert DVD error message. Any help on this would be much appreciated.